Similac 360 Total Care Infant Formula
Similac · Infant (0–12 months)
Similac 360 Total Care is Abbott's most advanced routine infant formula. It is the first and only leading brand to feature a blend of 5 Human Milk Oligosaccharides (HMOs) — 2'-FL, LNT, 3-FL, 6'-SL, and 3'-SL — which are prebiotics structurally identical to those found in breast milk. These HMOs are designed to support a baby's developing immune system and gut health. The formula is also palm olein oil-free, which has been shown to support softer stools and better calcium absorption. It is 100% lactose-based and contains no corn syrup.
0–12 months
At a glance
- Closest formula to breast milk from Similac
- Includes 5 Human Milk Oligosaccharides (HMOs) previously only found in breast milk
- Designed to support immune system, brain development, and digestive health
- Palm olein oil-free for improved calcium absorption
- Non-GMO (ingredients not genetically engineered)
- No corn syrup or artificial growth hormones
- Lactose-based carbohydrate source
- Available in multiple formats including Ready-to-Feed
Nutrition
Per 100 kcal unless otherwise noted
| Nutrient | Amount |
|---|---|
| Protein | 2.07 g |
| Fat | 5.6 g |
| Carbohydrates | 10.5 g |
| DHA | 8 mg |
| ARA | 16 mg |
| MFGM | Not added |
| Prebiotics | 5 HMOs (2'-FL, LNT, 3-FL, 6'-SL, 3'-SL) |
| Iron | 1.8 mg |
Ingredients
Certifications & dietary info
Certifications
Dietary facts
- Palm oil free
- Yes
- Corn syrup free
- Yes
- Soy free
- No
- Organic
- No
- Carbohydrate source
- lactose
Contains
Other tags
Safety & recall history
October 2022 (RTF cap issues)
- 2022-10-14 voluntary
Potential cap issues on 2 fl oz Ready-to-Feed bottles
2 fl oz Ready-to-Feed bottles from certain lots only — powdered product not affected
FDA enforcement status: Terminated
View FDA source ↗
Origin & manufacturing
- Country of origin
- USA
- Manufactured in
- USA
- FDA registered
- Yes
Why parents consider it
Most advanced HMO blend (5 different HMOs). Palm olein oil-free. Lactose-based (no corn syrup). Widely available in almost every major US retailer. Trusted brand with long history in the US market.
Worth knowing
Contains soy oil and soy lecithin (not soy-free). Not organic. Higher price than Similac Advance or other 'standard' lines. Historical recall issues at the Sturgis facility have caused trust concerns for some.
Our plain-English take
Similac 360 Total Care is the flagship 'science-forward' formula in the US. The inclusion of 5 HMOs is a genuine innovation that bridges the gap between traditional formula and breast milk. If you aren't strictly looking for organic and want the most researched ingredients, this is a top contender.
Recall history
Last reviewed
Where to Buy
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