Enfamil NeuroPro Infant Formula vs Similac 360 Total Care Infant Formula
Enfamil NeuroPro Infant Formula and Similac 360 Total Care Infant Formula are both cow-milk infant formulas and both non-organic. Both are standard everyday formulas, suitable for healthy infants without special dietary needs. Both formulas share lactose as their primary carbohydrate source. Similac 360 Total Care Infant Formula is the more affordable option at $1.70/oz per ounce — about $0.18/oz less than Enfamil NeuroPro Infant Formula ($1.88/oz). Use the full comparison table below to weigh nutrition, allergens, certifications, and recall history before deciding which formula is right for your baby.
Enfamil NeuroPro Infant Formula
$1.88/oz
Similac 360 Total Care Infant Formula
$1.70/oz
Where They Differ Most
| Field | Enfamil NeuroPro | Similac 360 Total Care |
|---|---|---|
| Price (approx. per oz) | $1.88 | $1.70 |
| Milk / form | cow-milk · powder | cow-milk · powder |
| Probiotics | — | — |
| Palm oil | Contains palm oil | Palm oil free |
Side-by-Side Comparison
included not listed Verify current label
| Feature | Enfamil NeuroPro Infant Formula $1.88/oz | Similac 360 Total Care Infant Formula $1.70/oz Lowest price |
|---|---|---|
| At a glance | ||
| Price | $1.88/oz · $38.99 · 20.7 oz | $1.70/oz · $34.99 · 20.6 oz |
| Age range | 0–12 months | 0–12 months |
| Milk / form | cow milk · powder | cow milk · powder |
| Specialty | standard | standard |
| Organic | No | No |
| Recall history | None on record | 1 recall: Potential cap issues on 2 fl oz Ready-to-Feed bottles |
| Nutrition | ||
| Protein | 2.1 g | 2.07 g |
| Fat | 5.3 g | 5.6 g |
| Carbohydrates | 11.3 g | 10.5 g |
| DHA / ARA | 17 mg / 25 mg | 8 mg / 16 mg |
| Prebiotics | GOS, PDX, 2'-FL HMO | 5 HMOs (2'-FL, LNT, 3-FL, 6'-SL, 3'-SL) |
| Probiotics | — | — |
| Iron | 1.8 mg | 1.8 mg |
| Ingredients & dietary | ||
| Carb source | lactose | lactose |
| Palm oil free | No | Yes |
| Corn syrup free | Yes | Yes |
| Soy free | No | No |
| Allergens | milk, soy | milk, soy |
| Certifications | Halal, Kosher Dairy | Kosher, Halal |
| Editorial notes | ||
| Key highlights | Features MFGM (Milk Fat Globule Membrane) to support cognitive development, Includes expert-recommended DHA (0.32% of total fatty acids), Contains 2'-FL HMO for immune system support, Dual prebiotic blend (GOS and PDX) for digestive health, The #1 brand recommended by pediatricians, No corn syrup or artificial growth hormones, Lactose-based carbohydrate source, Clinically proven to support brain building | Closest formula to breast milk from Similac, Includes 5 Human Milk Oligosaccharides (HMOs) previously only found in breast milk, Designed to support immune system, brain development, and digestive health, Palm olein oil-free for improved calcium absorption, Non-GMO (ingredients not genetically engineered), No corn syrup or artificial growth hormones, Lactose-based carbohydrate source, Available in multiple formats including Ready-to-Feed |
| Pros | Includes MFGM for brain support, Higher DHA levels than many other US brands, Contains 2'-FL HMO and dual prebiotics, Lactose-based (no corn syrup), Available everywhere and highly recommended by pediatricians | Most advanced HMO blend (5 different HMOs), Palm olein oil-free, Lactose-based (no corn syrup), Widely available in almost every major US retailer, Trusted brand with long history in the US market |
| Cons | Contains palm olein oil, Contains soy oil and soy lecithin, Not organic, Higher price than standard Enfamil Infant | Contains soy oil and soy lecithin (not soy-free), Not organic, Higher price than Similac Advance or other 'standard' lines, Historical recall issues at the Sturgis facility have caused trust concerns for some |
| Origin | USA; manufactured in USA | USA; manufactured in USA |
| FDA registered | Yes | Yes |
Prices, nutrition values, and ingredient details are approximate and based on data collected at the time this page was last updated. Always verify the current label and price on the retailer's site.
Buying Options
Enfamil NeuroPro Infant Formula
Similac 360 Total Care Infant Formula
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Frequently Asked Questions
Which is cheaper per ounce — Enfamil NeuroPro Infant Formula or Similac 360 Total Care Infant Formula?
Similac 360 Total Care Infant Formula is the more affordable option at $1.70/oz, compared to $1.88/oz — a difference of about $0.18 per ounce. Over a month of feeding, that adds up noticeably. Always compare bulk/subscription prices for the best value.
Is either formula organic or corn-syrup free?
Neither Enfamil NeuroPro Infant Formula nor Similac 360 Total Care Infant Formula is certified organic — if organic is important to you, consider formulas like Bobbie, Kendamil Organic, or HiPP instead. Both are corn-syrup free.
Are both formulas FDA-registered?
Yes — both Enfamil NeuroPro Infant Formula and Similac 360 Total Care Infant Formula are registered with the FDA under the Infant Formula Act, which requires manufacturers to notify the FDA before marketing new formulas in the United States. Note that European formulas sold by US importers may not appear on the FDA's domestic registration list, even if they meet or exceed EU regulatory standards.
Which formula is better for a sensitive stomach?
Both Enfamil NeuroPro Infant Formula and Similac 360 Total Care Infant Formula are standard formulas, not specifically marketed for sensitive stomachs. If your baby has digestive sensitivities, you may want to look at gentler or sensitive formulas. That said, some babies tolerate one formula better than another even within the standard category — consult your pediatrician before switching.
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Compare more than two →Medical disclaimer
Not medical advice. The information on this page is for general informational purposes only and is not a substitute for professional medical advice. Formula choices should be made in consultation with your pediatrician or a qualified healthcare provider, taking into account your baby's individual health needs. Always read product labels and follow preparation instructions carefully.