Similac 360 Total Care Infant Formula vs Similac Sensitive Infant Formula
Similac 360 Total Care Infant Formula and Similac Sensitive Infant Formula are both cow-milk infant formulas and both non-organic. Similac 360 Total Care Infant Formula is formulated as a standard formula, while Similac Sensitive Infant Formula targets sensitive needs — so they appeal to different families depending on your baby's digestive sensitivities. On ingredients, Similac 360 Total Care Infant Formula uses lactose as its primary carbohydrate, whereas Similac Sensitive Infant Formula relies on a mixed carb blend — a meaningful difference for parents who prefer to avoid corn-syrup solids. Similac 360 Total Care Infant Formula is the more affordable option at $1.70/oz per ounce — about $0.22/oz less than Similac Sensitive Infant Formula ($1.92/oz). Use the full comparison table below to weigh nutrition, allergens, certifications, and recall history before deciding which formula is right for your baby.
Similac 360 Total Care Infant Formula
$1.70/oz
Similac Sensitive Infant Formula
$1.92/oz
Where They Differ Most
| Field | Similac 360 Total Care | Similac Sensitive |
|---|---|---|
| Price (approx. per oz) | $1.70 | $1.92 |
| Milk / form | cow-milk · powder | cow-milk · powder |
| Probiotics | — | — |
| Palm oil | Palm oil free | Palm oil free |
Side-by-Side Comparison
included not listed Verify current label
| Feature | Similac 360 Total Care Infant Formula $1.70/oz Lowest price | Similac Sensitive Infant Formula $1.92/oz |
|---|---|---|
| At a glance | ||
| Price | $1.70/oz · $34.99 · 20.6 oz | $1.92/oz · $23.99 · 12.5 oz |
| Age range | 0–12 months | 0–12 months |
| Milk / form | cow milk · powder | cow milk · powder |
| Specialty | standard | sensitive |
| Organic | No | No |
| Recall history | 1 recall: Potential cap issues on 2 fl oz Ready-to-Feed bottles | 1 recall: Potential Cronobacter sakazakii and Salmonella contamination at Sturgis, MI facility |
| Nutrition | ||
| Protein | 2.07 g | 2.1 g |
| Fat | 5.6 g | 5.4 g |
| Carbohydrates | 10.5 g | 10.9 g |
| DHA / ARA | 8 mg / 16 mg | 15 mg / 30 mg |
| Prebiotics | 5 HMOs (2'-FL, LNT, 3-FL, 6'-SL, 3'-SL) | FOS |
| Probiotics | — | — |
| Iron | 1.8 mg | 1.8 mg |
| Ingredients & dietary | ||
| Carb source | lactose | mixed |
| Palm oil free | Yes | Yes |
| Corn syrup free | Yes | No |
| Soy free | No | No |
| Allergens | milk, soy | milk, soy |
| Certifications | Kosher, Halal | Kosher, Halal |
| Editorial notes | ||
| Key highlights | Closest formula to breast milk from Similac, Includes 5 Human Milk Oligosaccharides (HMOs) previously only found in breast milk, Designed to support immune system, brain development, and digestive health, Palm olein oil-free for improved calcium absorption, Non-GMO (ingredients not genetically engineered), No corn syrup or artificial growth hormones, Lactose-based carbohydrate source, Available in multiple formats including Ready-to-Feed | Designed for fussiness and gas due to lactose sensitivity, Milk protein isolate based — reduced lactose compared to standard formulas, Includes OptiGRO blend: DHA, Lutein, and Vitamin E, Palm olein oil free (uses high oleic safflower, soy, and coconut oils), No artificial growth hormones, Trusted brand with long history in the US market |
| Pros | Most advanced HMO blend (5 different HMOs), Palm olein oil-free, Lactose-based (no corn syrup), Widely available in almost every major US retailer, Trusted brand with long history in the US market | Reduces gas and fussiness associated with lactose sensitivity, Palm olein oil free for better calcium absorption, Contains DHA, Lutein, and Vitamin E for development, Widely available in most US retailers, Easy-to-digest milk protein isolate |
| Cons | Contains soy oil and soy lecithin (not soy-free), Not organic, Higher price than Similac Advance or other 'standard' lines, Historical recall issues at the Sturgis facility have caused trust concerns for some | Contains corn syrup and sugar as primary carbohydrate sources, Not suitable for babies with cow's milk protein allergy (CMPA), Higher price point than Similac Advance (Standard), Contains soy oil |
| Origin | USA; manufactured in USA | USA; manufactured in USA |
| FDA registered | Yes | Yes |
Prices, nutrition values, and ingredient details are approximate and based on data collected at the time this page was last updated. Always verify the current label and price on the retailer's site.
Buying Options
Similac 360 Total Care Infant Formula
Similac Sensitive Infant Formula
We may earn a commission if you buy through these links at no extra cost to you. Affiliate disclosure . Prices are approximate and may have changed — confirm the current price on the retailer's site.
Frequently Asked Questions
Which is cheaper per ounce — Similac 360 Total Care Infant Formula or Similac Sensitive Infant Formula?
Similac 360 Total Care Infant Formula is the more affordable option at $1.70/oz, compared to $1.92/oz — a difference of about $0.22 per ounce. Over a month of feeding, that adds up noticeably. Always compare bulk/subscription prices for the best value.
Is either formula organic or corn-syrup free?
Neither Similac 360 Total Care Infant Formula nor Similac Sensitive Infant Formula is certified organic — if organic is important to you, consider formulas like Bobbie, Kendamil Organic, or HiPP instead. Similac 360 Total Care Infant Formula is corn-syrup free; Similac Sensitive Infant Formula contains corn-syrup solids.
Are both formulas FDA-registered?
Yes — both Similac 360 Total Care Infant Formula and Similac Sensitive Infant Formula are registered with the FDA under the Infant Formula Act, which requires manufacturers to notify the FDA before marketing new formulas in the United States. Note that European formulas sold by US importers may not appear on the FDA's domestic registration list, even if they meet or exceed EU regulatory standards.
Which formula is better for a sensitive stomach?
Similac Sensitive Infant Formula is specifically formulated for sensitive needs, making it the better choice for a sensitive stomach. Similac 360 Total Care Infant Formula is a standard formula. If your baby shows signs of gas, fussiness, or intolerance, Similac Sensitive Infant Formula is worth discussing with your pediatrician.
Related comparisons
Compare more formulas
Need to compare three formulas at once, or explore a pairing not listed here? Use our interactive compare tool.
Compare more than two →Medical disclaimer
Not medical advice. The information on this page is for general informational purposes only and is not a substitute for professional medical advice. Formula choices should be made in consultation with your pediatrician or a qualified healthcare provider, taking into account your baby's individual health needs. Always read product labels and follow preparation instructions carefully.